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Image Search Results
Journal: Asian Pacific Journal of Cancer Prevention : APJCP
Article Title: Unexpected Lower Expression of Oncoprotein Gankyrin in Drug Resistant ABCG2 Overexpressing Breast Cancer Cell Lines
doi: 10.22034/APJCP.2017.18.12.3413
Figure Lengend Snippet: The Expression of ABCG2 at mRNA Level in MCF-7 Derived Breast Cancer Cell Lines. ABCG2 mRNA level is compared between drug resistance cell line MCF-7/MX and its parental non-resistance MCF-7 cells. Real-time RT-PCR analysis was performed on total RNA extracted from cells. Values were normalized to the β-actin content of samples and expressed as mean ±SEM (n = 3). Statistical significance was calculated by one-way Analysis of variance (ANOVA) and Tukey’s post-hoc; ***p < 0.001 compared with the non-resistance parental cell line.
Article Snippet:
Techniques: Expressing, Derivative Assay, Quantitative RT-PCR
Journal: International Journal of Clinical Practice
Article Title: Machine Learning-Based Integrated Analysis of PANoptosis Patterns in Acute Myeloid Leukemia Reveals a Signature Predicting Survival and Immunotherapy
doi: 10.1155/2024/5113990
Figure Lengend Snippet: Identification of the diverse patterns based on the PANoptosis gene list. (a) A total of 226 PANoptosis-related genes belonging to necroptosis, apoptosis, and pyroptosis were collected for downstream analysis. (b) The univariate Cox regression analysis and Spearman's sum rank test were performed in the HOVON cohort, which was set as the training cohort. 28 genes with prognostic prediction were screened out with p value <0.05. (c) An interaction network of prognostic PANoptosis-related genes. (d) The 618 patients in HOVON cohort were divided into three clusters, according to the consensus clustering analysis based on the transcriptome profile of PANoptosis-related genes. (e) The KM curves showing the differential overall survival among the three subgroups. (f) A heat map showing the expression of the prognostic PANoptosis related genes in different subgroups. The two-sided p value <0.05 was considered significant for all statistical analyses and shown as ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p < 0.0001.
Article Snippet:
Techniques: Expressing